Mediterranean Cruises from Southampton

The Best of the Mediterranean : 2025, 2026 & 2027 Cruises from Southampton

Portofino, Italy

Set Sail for Sun‑Kissed Shores on a Mediterranean Cruise

It’s easy to see why a Mediterranean cruise from Southampton is a favourite choice for UK travellers. Step aboard without the hassle of flying and sail south through the Bay of Biscay, past Gibraltar and into the sun-soaked Mediterranean. Most itineraries explore Spain, France and Italy, while longer sailings of 19–31 nights venture further east to Greece and Turkey. Wherever you go, expect glamorous resorts, historic cities and idyllic islands, all set against a warm, balmy climate.

UNESCO Sites

Pay tribute to ancient civilisations and admire monuments such as the Colosseum in Rome, Castel Nuovo in Naples, or the Alhambra in Granada. The Mediterranean is like an open-air museum, filled with UNESCO World Heritage Sites that bring history to life under the sun.

View Cruises >

Barcelona Couple
Barcelona, Spain

Explore Barcelona’s vibrant culture, stunning architecture, and seaside charm.

Lady sightseeing in Florence, Italy
Florence, Italy

Florence enchants with Renaissance treasures, from the iconic Duomo to Michelangelo’s David, and boutique-lined streets perfect for strolling.

Rome's Trevi Fountain
Rome, Italy

Uncover ancient wonders, vibrant streets, and Italian charm in Rome.

Culture & History

When you’ve had your fill of cathedrals and castles, dive into the culture that defines the Med. Stroll along Barcelona’s Las Ramblas, explore the Gothic Quarter, or step inside Florence’s breathtaking Duomo. Wander through the old town of Valletta, Malta’s fortress capital, or take in the vibrancy of Marseille’s Old Port. For something modern, explore Bilbao’s Guggenheim Museum or enjoy a shopping spree in stylish Milan.

Nature & Coastlines

The Mediterranean is famed for golden beaches, pine-clad hills and sparkling seas. Discover the dramatic landscapes of southern Spain, relax on the sandy shores of the Balearic Islands, or explore the rugged beauty of Corsica and Sardinia. Italy’s Amalfi Coast is another highlight, with pastel-coloured villages clinging to cliffs above turquoise seas. Whether you’re seeking a tranquil haven or lively waterfront festivals, you’ll be welcomed with Mediterranean warmth and hospitality.

Food, Glorious Food!

Sightseeing will soon build an appetite, and the Med is a foodie’s paradise. Think pizza in Naples, pintxos in Barcelona, seafood paella in Valencia or fresh pasta in Liguria. Pair your meal with local wine on a tasting in Bordeaux or Lisbon before you reach the Med. Coffee culture is taken seriously here too - the perfect excuse to pause in a café and watch the world go by. A cruise through the Mediterranean is a chance to indulge, because life is full of pasta-bilities!

Set Sail on a Mediterranean Cruise from Southampton

Use our search filters below to find your perfect Mediterranean cruise, book online today at Southampton Cruise Centre or call our cruise experts on 02380 658 386

We found